Effects of Music on Psychophysiological Responses and Opioid Dosage in Patients Undergoing Total Knee Replacement Surgery


Japan Journal of Nursing Science




AIM: The present authors examined the effects of listening to music on psychophysiological parameters (blood pressure, heart rate, and respiratory rate) during preoperative and postoperative days and determined whether listening to music could lower pain intensity and opioid dosage during postoperative days in patients who underwent total knee replacements. METHODS: This was a two group repeated measures design for 30 subjects aged 53-85 years who were scheduled for total knee replacement. Subjects were randomly assigned to either a music group or a control group. Psychophysiological parameters were obtained from patients' monitors. A visual analog scale was used to assess postoperative pain. Opioid dosage was recorded and converted to standardized units. Mann-Whitney U-test and generalized estimating equation analysis were used to compare groups. RESULTS: Respiratory rates while in the surgical waiting area were lower for the music group than for the control group (P = 0.02). There was no significant difference between these groups for blood pressure, heart rate, pain intensity, or opioid dosage. However, a within-group comparison showed that systolic blood pressure in the music group was significantly and consistently decreased during postoperative recovery (Wald = 9.21, P = 0.007). CONCLUSION: These results suggest that listening to music stabilized systolic blood pressure in patients during postoperative recovery. However, the effects of music on psychophysiological parameters, pain intensity, and opioid dosage in a surgical setting require further research.

Music and Health Institute Terms

Analgesic Intake; Blood Pressure; Heart Rate; Hospital Setting; Hospitalized Patients; Medication Use; Music Listening; Music Medicine; Opioid Intake; Orthopedic Surgery; Pain; Pain Management and Control; Pain Score or Rating; Pain Severity; Postoperative Pain; Postoperative Patients; Recorded Music Listening; Respiratory Rate; Self-Report Measures; Surgery; Surgical Patients; Visual Analog Scale (VAS); Vital signs

Indexed Terms

Elderly; Opioid Analgesics; Arthroplasty, Replacement, Knee; Dose-Response Relationship, Drug; Postoperative Pain; Psychophysics; opioids; pain intensity; psychophysiology; total knee replacement

Study Type

Randomized Controlled Trial; Quantitative Methods

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