Effects of Mindfulness-based Stress Reduction Combined With Music Therapy on Pain, Anxiety, and Sleep Quality in Patients With Osteosarcoma


H. Liu
X. Gao
Y. Hou


Brazilian Journal of Psychiatry




OBJECTIVES: To evaluate the effects of mindfulness-based stress reduction (MBSR) combined with music therapy (MT) on clinical symptoms in patients with osteosarcoma. METHODS: Patients diagnosed with osteosarcoma were assessed for eligibility. A total of 101 patients were ultimately randomized into the intervention and control groups. Both groups received routine care. Eight sessions of MBSR and MT psychotherapy were conducted in the intervention group, while the control group received no psychological intervention. Patients were assessed regarding pain, anxiety, and sleep quality at two distinct stages: before and after the intervention. RESULTS: There were no significant differences in sociodemographic and clinical parameters between the intervention and control groups at baseline. The intervention program significantly alleviated psychological and physiological complications in patients with osteosarcoma. Specifically, the study revealed that 8 weeks of the combined MBSR/MT intervention effectively reduced pain and anxiety scores and improved the quality of sleep in patients. CONCLUSION: MBSR combined with MT significantly alleviated clinical symptoms, and could be considered a new, effective psychotherapeutic intervention for patients with osteosarcoma.

Music and Health Institute Terms

Anxiety; Anxiety Scales; Cancer; Functional Status; Music in Combination with Other Techniques; Music Listening; Music Therapy; Pain; Pain Management and Control; Pain Score or Rating; Psychological Outcomes; Receptive Music Methods; Recorded Music Listening; Self-Report Measures; Sleep Quality; Stress

Indexed Terms

Adolescents; Anxiety; Bone Neoplasms; Children; Mindfulness; Osteosarcoma; Pain; Pain Measurement; Quality of Life; Sleep; Stress; Surveys and Questionnaires; Test Anxiety Scale; Time Factors

Study Type

Quantitative Methods; Randomized Controlled Trial

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Document Type