Decomposing the Effects of Familiarity With Music Cues on Stride Length and Variability in Persons With Parkinson's Disease: On the Role of Covariates
Journal
International Journal of Environmental Research and Public Health
Year
2023
Abstract
This systematic review and meta-analysis examined previous studies on music-based interventions for individuals with Parkinson’s disease (PD). The effectiveness of the interventions on various motor and non-motor outcomes was evaluated. This review was conducted by searching PubMed, CINAHL, PsycINFO, and Cochrane Library CENTRAL prior to June 2022 for randomized controlled trial (RCT) and controlled clinical trial (CCT) studies published in English. Data were expressed as weighted/standardized mean difference (MD/SMD) with 95% confidence intervals (CI). I2 index was used for heterogeneity. The initial search identified 745 studies, and 13 studies involving 417 participants with PD which met the inclusion criteria included in this review. The results of the meta-analysis revealed that music-based interventions can significantly improve walking velocity (MD = 0.12, 95% CI = 0.07~0.16, p < 0.00001), stride length (MD = 0.04, 95% CI = 0.02~0.07, p = 0.002), and mobility (MD = −1.05, 95% CI = −1.53~−0.57, p < 0.0001). However, the results did not support significant effects for music-based interventions on cadence (MD = 3.21, 95% CI = −4.15~10.57, p = 0.39), cognitive flexibility (MD = 20.91, 95% CI = −10.62~52.44, p = 0.19), inhibition (SMD = 0.07, 95% CI = −0.40~0.55, p = 0.76), and quality of life (SMD = −0.68, 95% CI= −1.68~0.32, p = 0.18). The findings suggest that music-based interventions are effective for the improvement of some motor symptoms, but evidence for non-motor symptoms is limited. Further high-quality studies with a larger sample size are required to obtain the robust effects of music-based interventions on various outcomes among patients with PD.
Music and Health Institute Terms
Cognitive Abilities; Gait; Mobility; Music Therapy; Neurodegenerative Disorders; Parkinson's Disease; Quality of Life; Symptom Management; Wellness and Well-Being
Indexed Terms
Parkinson Disease; meta-analysis; motor symptoms; non-motor symptoms; Parkinson’s disease; Randomized Controlled Trials as Topic
Study Type
Meta-Analysis; Systematic Review; Quantitative Methods
Document Type
Article
Recommended Citation
Lee, H., & Ko, B. (2023). Decomposing the Effects of Familiarity With Music Cues on Stride Length and Variability in Persons With Parkinson's Disease: On the Role of Covariates. International Journal of Environmental Research and Public Health, 20 (2) Retrieved from https://remix.berklee.edu/mhi-citations/1493