Music Recognition in Frontotemporal Lobar Degeneration and Alzheimer Disease

Journal

Cognitive and Behavioral Neurology

Year

2011

Abstract

OBJECTIVE: To compare music recognition in patients with frontotemporal dementia, semantic dementia, Alzheimer disease, and controls and to evaluate the relationship between music recognition and brain volume. BACKGROUND: Recognition of familiar music depends on several levels of processing. There are few studies about how patients with dementia recognize familiar music. METHODS: Subjects were administered tasks that assess pitch and melody discrimination, detection of pitch errors in familiar melodies, and naming of familiar melodies. RESULTS: There were no group differences on pitch and melody discrimination tasks. However, patients with semantic dementia had considerable difficulty naming familiar melodies and also scored the lowest when asked to identify pitch errors in the same melodies. Naming familiar melodies, but not other music tasks, was strongly related to measures of semantic memory. Voxel-based morphometry analysis of brain magnetic resonance imaging showed that difficulty in naming songs was associated with the bilateral temporal lobes and inferior frontal gyrus, whereas difficulty in identifying pitch errors in familiar melodies correlated with primarily the right temporal lobe. CONCLUSIONS: The results support a view that the anterior temporal lobes play a role in familiar melody recognition, and that musical functions are affected differentially across forms of dementia.

Music and Health Institute Terms

Alzheimer's and Related Dementias; Cognitive Abilities; Elderly; Memory; Music and Cognition; Music Cognition; Neurodegenerative Disorders

Indexed Terms

Elderly; Alzheimer Disease; Auditory Perception; Brain; Brain Mapping; Frontotemporal Lobar Degeneration; Magnetic Resonance Imaging; Neuropsychological Tests; Recognition, Psychology

Study Type

Editorial, Opinions, Position Papers

PubMed ID

21617528

Document Type

Article

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