Salivary cortisol and alpha-amylase as stress markers to evaluate an individualized music intervention for people with dementia: feasibility and pilot analyses
Journal
BMC Research Notes
Year
2024
Abstract
OBJECTIVES: We investigated salivary biomarkers of stress, more specifically, cortisol and alpha-amylase, to evaluate effects of individualized music listening (IML) in people with dementia. METHOD: Participants were N = 64 nursing home residents with dementia (meanage = 83.53 ± 7.71 years, 68.8% female). Participants were randomly assigned to either listening to their favorite music every other day for a period of six weeks (intervention), or standard care (control). Using the Saliva Children`s Swab (SCS), saliva was collected before, after, and 20 min after IML sessions at the beginning and end of the intervention period for the analysis of salivary alpha-amylase and cortisol. RESULTS: Using the SCS was feasible in people with dementia. Nevertheless, there was no effect of IML on salivary stress markers. DISCUSSION: Although using SCS was feasible, active patient engagement is required. Future studies need to corroborate findings in larger samples. TRIAL REGISTRATION: German Clinical Trials Register: DRKS00015641, ISRCTN registry: ISRCTN59052178.
Music and Health Institute Terms
Neurodegenerative Disorders; Alzheimer's and Related Dementias; Stress; Physiological Measures; Observational Measures; Long-Term Care Facility; Music Medicine; Music Listening; Cognitive Abilities; Psychological Outcomes
Indexed Terms
ANS; Elderly; Elderly; Alpha-amylase; Biomarkers; Cognitive impairment; Cortisol; Dementia; Feasibility Studies; HPA axis; Hydrocortisone; Non-pharmacological intervention; Pilot Projects; Psychobiology of stress; Salimetric’s children’s Swab; Saliva; Stress; alpha-Amylases
Study Type
Randomized Controlled Trial; Quantitative Methods
PubMed ID
PMID: 39267193 PMCID: PMC11391792
Document Type
Article
Recommended Citation
Hillebrand, M. C., Sindermann, C., Montag, C., Wuttke, A., Heinzelmann, R., Haas, H., & Wilz, G. (2024). Salivary cortisol and alpha-amylase as stress markers to evaluate an individualized music intervention for people with dementia: feasibility and pilot analyses. BMC Research Notes, 17 (1), 258. Retrieved from https://remix.berklee.edu/mhi-citations/1767
