A live-music therapy protocol for pain management in advanced cancer: The MSPD pilot study

Journal

Journal of Pain and Symptom Management

Year

2025

Abstract

BACKGROUND: Patients with advanced cancer often experience disease- and treatment-related pain. Previous studies have shown that music therapy can help manage pain. The aim of this pilot study was to evaluate the effects of a live-music therapy protocol, delivered by a trained music therapist, to induce relaxation in patients, allowing for real-time patient management and tailored sessions. METHODS: This prospective, exploratory study included patients with advanced cancer with a pain score ≥3/10 before the intervention (NCT05315427). A trained music therapist performed a single music intervention to induce a state of deep relaxation. We evaluated the effect of music therapy on pain using a numerical rating scale before and after intervention, taking into account analgesic intake before the session. Secondary objectives included symptoms assessment, patient satisfaction, and interest in future sessions. RESULTS: Forty patients were included. Pain significantly decreased from 4.9 (95% CI: 4.3-5.4) to 3.5 (95% CI: 2.9-4.2) (P < 0.0001) following music intervention, regardless of analgesic intake. We observed a significant reduction in fatigue (6.2 vs. 4.3) and anxiety (2.7 vs. 1.0) (P < 0.0001), and an improvement in well-being (5.2 vs. 3.3) (P < 0.0001). The mean satisfaction score was 8.9 (95% CI: 8.4- 9.3), and 95% of patients were willing to have a second session. CONCLUSIONS: A single session of music-induced relaxation led to a short-term reduction of pain in patients with advanced cancer while improving their symptoms. Future research should confirm the efficacy of our intervention, assess its long-term effects, and explore the benefits of a multisession program.

Music and Health Institute Terms

Cancer; Cancer Pain; Chronic Pain; Fatigue; Music Therapy; Pain; Pain Management and Control; Relaxation; Symptom Management; Wellness and Well-Being ((Outcome))

Indexed Terms

Elderly; Elderly; pain; oncology; Pain Measurement; Patient Satisfaction; Prospective Studies; Pilot Projects; live music; Cancer Pain; Neoplasms; Pain Management; Clinical Trials as Topic; relaxation

Study Type

Quasi-Experimental Study; Quantitative Methods

Document Type

Article

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